What is Tramadol is a prescription pain reliever. It belongs to a class of pain drugs called opiate narcotic analgesics, which change the way how your brain responds to pain. Tramadol works in a similar way to substances in your brain called endorphins. Endorphins bind to receptors and these receptors then decrease the pain senses that your body sends to your brain.

Therapeutic indications

Tramadol is used to manage moderate to moderately severe pain in adults. Tramadol may be used as part of combination therapy with other medications. Tramadol should be taken exactly as prescribed. Follow all directions your doctor gave you and never take Tramadol in larger amounts, or for longer than prescribed. Inform your doctor if Tramadol seems to stop working as well in relieving your pain.


Avoid the use of Tramadol in the following cases:

  • if you are allergic to it;
  • if you have asthma or breathing problems. Tramadol can slow or stop your breathing;
  • if you are suicidal or prone to addiction, such as drug or alcohol abuse. You should consider taking non-narcotic analgesics instead;
  • if you take antidepressants or another opioid pain reliever;
  • if you have a blockage in your stomach or intestines;
  • if you have a history of emotional disturbances (including depression);
  • if you have recently used alcohol, sedatives, tranquilizers, narcotic medication, or an MAO inhibitor in the past 14 days (isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others).

Be aware that Tramadol may be habit-forming. Also, Tramadol should not be given to a child younger than 12 years old.

What is Tramadol

Side effects

Tramadol can have side effects. If you have any side effects from Tramadol, immediately inform your doctor about it. The most common side effects are:

  • dizziness;
  • nausea;
  • constipation;
  • headache;
  • seizures;
  • trouble breathing;
  • symptoms of serotonin syndrome: agitation, fever, nausea, muscle stiffness, lack of coordination, or loss of consciousness;
  • chest pain;
  • rapid heartbeat;
  • extreme drowsiness;
  • fainting;
  • swelling of the face, tongue, throat, or extremities;
  • hallucinations;
  • severe rash;
  • thoughts of suicide.

Less common side effects of Tramadol are:

  • sleepiness;
  • vomiting;
  • itching;
  • sweating;
  • feeling agitated, nervous, or high;
  • indigestion;
  • dry mouth;
  • diarrhea;
  • sleeplessness;
  • tremor;
  • loss of appetite.

It is always recommended to consult a doctor if you encounter any of the side effects.

People over the age of 65, may be at higher risk for side effects to appear, especially digestive side effects like constipation. People over the age of 75 may have to take a lower dose than is typically prescribed.

Serious side effects may occur to patients with overweight, malnourished, or debilitated. Also, you must be aware, that long-term use of opioid medication may affect fertility (ability to have children) in men or women.

Remember to always keep Tramadol and all other medicines out of the reach of children. Never share your medicines with other people. It’s extremely important that you use Tramadol exactly as prescribed by your doctor. Don’t take more or less.

Tramadol is also known under the trade names: Ultram, Conzip, Rybix ODT, Ultram ER, Invodol, Mabron, Maneo, Marol, Maxitram, Oldaram, Tilodol, Tradorec, Tramquel, Tramulief, Zamadol, Zeridame, and Zydol.