Zopiclone 7.5mg Tablets (ZOP)

£20.00£80.00

Zopiclone (Zop-pee-kloan) 7.5 mg is an oral drug used to treat sleeping disorders.The dosage of Zop 7.5 mg will depends upon person to person and their condition of sleeping disorders. Reducing your dose Zop 7.5 mg little by little after some time may reduces the chances of having specific complications. It is vital to have a sound sleep while acquiring Zop 7.5 mg you will be able to have that sleep.sleeping following acquiring Zopiclone. In case your sleeping can be interrupted prior to this time around offers handed down. You must not drink alcohol during the dose of this pill. Supertramadol.com offer different pills at discounted rate globally. We provide high quality and genuine products to our customers on time at the right place with full security of the drug. So that client will be able to get their pills without any damage. You can buy Zop 7.5 mg from SuperTramadol.com just by placing an order with free registration.
Name of the medicinal product

Zopiclone 7.5mg tablets

Qualitative and quantitative composition

Each tablet contains 7.5mg of zopiclone

Each tablet also contains 32.0mg Lactose Monohydrate

For a full list of excipients, see section 6.1.

Pharmaceutical form

Film-coated tablet

SKU: Zopiclone7.5mgTablets Category:

Description

What is Zopiclone?

Zopiclone belongs to the group of medicines called Central Nervous System (CNS) depressants. Because of its calming effect on the brain, Zopiclone is commonly used to treat insomnia. It helps you fall asleep more quickly, improves the quality of your sleep and stops waking up during the night or too early in the morning. Zopiclone also helps in case of severe problems of sleep due to mood or mental health problems.

Zopiclone is ‘’non benzodiazepine’’ agonist of benzodiazepine receptors. It also has a sedative, anxiolytic, muscle-relaxing center, anticonvulsant and amnesic properties. Zopiclone enhances GABA-ergic processes in the brain, interacting with the benzodiazepine receptors, as a result of the increased sensitivity of GABA-receptors to the neurotransmitter.

Being a derivative of benzodiazepine, Zopiclone shares an almost identical pharmacological profile to them. Zopiclone interacts with other parts of the benzodiazepine receptor than benzodiazepines. It acts as a full agonist, which in turn positively modulates benzodiazepine-sensitive GABAa receptors and enhances GABA binding at the GABAa receptors to produce Zopiclone’s subjective effects. Since GABA functions as the brain’s predominant inhibitory neurotransmitter, such activation of receptors results in the sedative and anxiolytic effects of Zopiclone.

Zopiclone generic and brand name

Zopiclone is also known under the brand names, such as: Zimovane, Imovane, Ran-Zopiclone, Rhovane Zimovane, Zileze, Zimoclone, Zopitan, Zorclone.

Why Zopiclone prescribed?

Zopiclone is recommended for the short-term treatment of insomnia. Your body can get used to it very quickly, and after some time it is unlikely to have the same effect. Your body can also become dependent on it. That is why Zopiclone is recommended for the short-term treatment of transient, situational and chronic insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings and early morning awakenings.

How Zopiclone works

Zopiclone belongs to the class of medications called sedative-hypnotics. Do not take Zopiclone when a full night’s sleep is not possible or before you would need to be active and functional. Wait at least 12 hours after taking this medication before driving or engaging in other activities that require mental alertness. Your body needs time to eliminate the medication from your system, otherwise, impaired judgment and memory lapses may occur. If you have been taking this medication regularly for an extended period of time, do not stop taking it suddenly without talking with your doctor.

Recommended doses of Zopiclone

Many things can affect the dose, such as body weight, other medical conditions, and other medications. The usual starting dose is 3.75 mg orally at night and it takes around 1 hour to work. That dose is recommended for elderly patients or if a patient has kidney or liver problems. Taking a lower dose in these cases reduces the risk of excessive sleepiness and other side effects. The recommended adult dose of Zopiclone is 7.5 mg. The maximum daily dose is 5 mg for seniors, people with reduced liver or kidney function, and people taking certain medications. In cases of severe insomnia the dose can be increased up to 15 mg. Please, bear in mind that this medication may be habit-forming and should be taken exactly as prescribed by your doctor.

What are the pharmacokinetic properties of the drug?

Zopiclone is rapidly absorbed, with a bioavailability of approximately 80%. The peak plasma concentration of 60 ng/mL is achieved within 90 minutes. The plasma protein binding of zopiclone has been reported to be between 45 and 80%. Zopiclone is partly metabolized in the liver to form an inactive N-demethylated derivative and an active N-oxide metabolite. Approximately 50% of the administered dose is decarboxylated and excreted via the lungs. Less than 7% of the drug is also excreted in unchanged form.

Which pregnancy category (A; B; C; D; X) has been assigned to Zopiclone?

Zopiclone should be avoided during pregnancy (especially in I and III trimesters, it may harm the developing baby) and is contraindicated for nursing mothers (Zopiclone penetrates into breast milk). If a woman uses Zopiclone in III trimesters of pregnancy there are possible violations of the nervous system in the newborn, the emergence of withdrawal syndrome. The use of Zopiclone can increase your risk of having a baby born early (before 37 weeks). If the woman is prescribed by a doctor took Zopiclone immediately prior to labor and delivery, it needs constant medical surveillance for the newborn. Immediately contact your doctor if you become pregnant while taking this medication. If you are currently planning to become pregnant, discuss this issue with your doctor.

How to use the drug?

Zopiclone should be used only for short periods of time, such as 1 or 2 days, and generally for no longer than 2-4 weeks. Please, note that this is a summary and does not have all possible information about Zopiclone. Current information is not individual medical advice and does not substitute for the advice of your doctor. Check the label on the medicine for exact dosing instructions. Take this medication exactly as prescribed.

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, and any medications you are taking, whether you are pregnant or breastfeeding, and any other significant facts about your health. These important factors may affect how you should use this medication.

How to store the drug?

Store Zopiclone at room temperature and protect it from light and moisture. Keep the drug out of the reach of children. Do not dispose of medicines into the wastewater (in the sink or in the toilet bowl) or in household waste. Ask your health care professional how to get rid of unused or outdated medications.

What special precautions should I follow while using Zopiclone?

Caution should be exercised in patients with a history of psychiatric disorders, drug abuse, kidney or liver disease, during pregnancy and breastfeeding. That is recommended to consult your doctor in the following cases:

•             If you are allergic to Zopiclone or any other ingredients present in the tablets;

•             If you have depression or a personality disorder;

•             If you are pregnant or planning to become pregnant;

•             If you are a nursing mother;

•             If you have a breathing disorder, such as asthma, sleep apnoea, or emphysema;

•             If you have a history of alcohol or substance abuse;

•             If you have impaired liver or kidney function due to a medical condition;

•             If you have Myasthenia Gravis (a disease characterized by muscle weakness);

•             If you are an elderly individual.

Zopiclone side effects

Side effects of Zopiclone, which may occur, are a bitter or metallic taste in your mouth, a dry mouth, daytime sleepiness, daytime restlessness or anxiety, double vision, dizziness, headaches, mental or mood changes, unsteadiness or clumsiness, confusion and difficulty with coordination. Impairment of driving skills with a resultant increased risk of road traffic accidents is probably the most important side effect. If you feeling sleepy or tired – don’t drive. Medical attention should be sought immediately in case signs of a serious allergic reaction to Zopiclone. 

What should I do in case of an overdose?

Symptoms of Zopiclone overdose may include one or more of the following symptoms: excessive drowsiness, slow, shallow breathing, pale skin, sudden onset of sweating, blurred vision and loss of consciousness. In case of emergency/overdose immediately contact your local poison control center or emergency room.  Respiration, pulse and blood pressure should be monitored and supported by general measures when necessary. Immediate gastric lavage should be performed.

Does Zopiclone have any interaction with other drugs?

Be aware that if you are taking these drugs together, such interaction can be harmful. There may be an interaction between Zopiclone and any of the following drugs:

  • Abiraterone;
  • anticonvulsants (medications used to prevent seizures; e.g., phenytoin, valproic acid, carbamazepine);
  • anti-anxiety medications (e.g., alprazolam, clonazepam, lorazepam);
  • antihistamines (e.g., cetirizine, doxylamine, diphenhydramine, hydroxyzine, loratadine);
  • antipsychotic medications;
  • “azole” antifungals (e.g., ketoconazole, itraconazole, voriconazole);
  • barbiturates (e.g., butalbital, pentobarbital, phenobarbital);
  • HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs; e.g., delaviridine, efavirenz, etravirine, nevirapine);
  • HIV protease inhibitors (e.g., darunavir, ritonavir, saquinavir).

Does Zopiclone have any interaction with diseases?

Discuss with your doctor how Zopiclone may affect your medical condition if you have depression, breathing problems, or liver impairment. Special monitoring may be needed for patients who suffer from muscle weakness due to myasthenia gravis or have poor respiratory reserves due to severe chronic bronchitis, emphysema, or another lung disease, or have sleep apnoea cannot safely take Zopiclone, nor can a patient with an untreated abnormality of the thyroid gland.

Additional information

Zopiclone 7.5mg Tablets

10, 50, 100