Bensedin (Diazepam) 10mg Tablets


Diazepam 10mg belongs to a group of drugs known as benzodiazepines which work by having a calming effect on various functions of the brain. Diazepam is used to treat a number of conditions including the following:

  • short-term relief of severe anxiety (an emotional state where you may sweat, tremble, feel anxious and have a fast heartbeat); this may occur alone or with difficulty in sleeping or mental health problems
  • severe insomnia (difficulty sleeping)
  • muscle spasms due to cerebral palsy or tetanus
  • symptoms of alcohol withdrawal
  • with other medicines to treat epilepsy (fits) or for convulsions caused by fever or poisoning
  • helping patients relax before surgery or dental procedures.

This medicine can also be used for children to treat night terrors (where they wake up screaming, crying and very upset), sleepwalking, to help them relax before surgery, to control muscle spasms/twitching as in tetanus and controlling tension and irritability in cerebral spasticity.

SKU: Bensedin(Diazepam)10mg Category:


What is Bensedin 10mg?

Bensedin belongs to a class of drugs from the group of benzodiazepines. It works by increasing the activity of a certain natural chemical in the body (gamma-aminobutyric acid – GABA) in the brain and nerves (central nervous system). Benzodiazepines produce a variety of effects by modulating the GABA subtype of the GABA receptor, the most prolific inhibitory receptor within the brain. This helps to reduce anxiety and seizure activity in the brain, to produce a calming effect and to get muscle relaxant effect due to the inhibition of spinal reflexes.

Bensedin acts to suppress seizures through interaction with y-aminobutyric acid (GABA) receptors of the A-type (GABAA). Benzodiazepines bind nonspecifically to benzodiazepine receptors which mediate sleep, affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. Binding of GABA to the site opens the chloride channel, resulting in a hyperpolarized cell membrane that prevents further excitation of the cell. It is believed that Bensedin enhances the actions of GABA by causing GABA to bind more tightly to the GABAA receptor.

Bensedin generic and brand name

Bensedin is also known under other brand names, such as: Diazepam, DAZ, Valium, Somaid, DIZY, Zepose, Stesolid, Diazeco, Digipam.

Why Bensedin prescribed?

Bensedin is prescribed for the treatment of anxiety disorders, neuroses, borderline states with symptoms of stress, restlessness, fear, sleep disturbance, withdrawal syndrome in chronic alcoholism, spastic conditions associated with lesions of the brain or spinal cord, myositis, bursitis, arthritis, accompanied by a voltage of skeletal muscle, as well as for epileptic seizures treatment especially to treat condition known as “status epileptucus”, premedication before anesthesia as a component of combined anesthesia, relief labor, premature birth, abruption placenta, tetanus.

Sometimes it also can be used with other medications to treat seizures. It provides anxiolytic, sedative, anticonvulsant and central muscle relaxant effect.  Bensedin may also be used for other conditions as determined by your doctor. 

How Bensedin works 

Bensedin is not recommended for daily use. Do not use it more than 5 times per month, unless your doctor told you to do that. Bensedin is commonly used as a short-term treatment. It should not be used for more than 3 months, because long-term chronic use of Bensedin can lead to addiction. It is recommended to wait at least 5 days, after you have used Bensedin 10mg, before taking it again.

Recommended doses of Bensedin 10mg

The daily dose of Bensedin ranges from 0.5 mg to 60 mg. Recommended doses of Bensedin are set individually and will be different for each patient. The information below includes only the average doses of Bensedin. Use Bensedin exactly as prescribed by your doctor – if your dose is different, do not change it unless your doctor tells you to do that. Do not increase your dose, do not take it more frequently or use it for a longer period of time than prescribed. The number of daily doses, the time allowed between doses and the length of the time you take the medicine – all that depends on your personal medical problem. The dose for adults, teenagers, and children 2 years of age and older is based on body weight. The dose for children younger than 2 years of age must be determined by the doctor. Do not share your medicine with other people. It may not be suitable for them and may harm them.

What are the pharmacokinetic properties of the drug?

Bensedin is rapidly and completely absorbed from the gastrointestinal tract. The peak plasma concentration is achieved in 30-90 minutes after oral ingestion. On IM injection, absorption is complete, though not always more rapid comparing to oral administration. Bensedin and its metabolites are highly bound to plasma protein (Bensedin 98%), cross the blood-brain and placental barriers and are also found in breast milk in concentrations approximately 1/10 of those in maternal plasma. Bensedin is metabolized in the liver and excreted by the kidneys – 70%.

Which pregnancy category (A; B; C; D; X) has been assigned to Bensedin 10mg?

Bensedin has been assigned to pregnancy category D by the FDA Pregnancy Risk Categories. The drug should not be used in the 1 trimester of pregnancy, except in cases of extreme necessity. It has been stated that there is an increased risk of congenital malformations and other developmental abnormalities associated with the use of benzodiazepine group of drugs.  It may cause neonatal flaccidity, respiratory and feeding difficulties, as well as hypothermia in children born to mothers who have been receiving benzodiazepines late in pregnancy. Special care should be taken if Bensedin was used during the time of labor and delivery. High single doses may produce irregularities in the fetal heart rate (FHR) and hypotonia, poor sucking, hypothermia and moderate respiratory depression in the neonate.

How to use the drug?

Traditional anti-anxiety drugs such as benzodiazepines are used in the treatment of anxiety disorders. Please, note that this is a summary and does not have all possible information about Bensedin. Current information is not individual medical advice and does not substitute for the advice of your doctor. Check the label on the medicine for exact dosing instructions. Take this medication exactly as prescribed. In case, you miss your regular dose of Bensedin, take it as soon as possible. If several hours have passed and if it is time to take the next dose, do not double the dose to catch up, unless directed by your doctor. Do not take two doses at once.

Avoid eating grapefruit or drinking grapefruit juice while being treated with Bensedin 10mg. Grapefruit juice can increase the number of certain medications in your bloodstream. Talk with your doctor or pharmacist for more details. Always inform your doctor if your condition persists or worsens. 

How to store the drug?

Store Bensedin at room temperature and keep it away from moisture. Keep the drug out of the reach of children. Do not dispose of medicines into the wastewater (in the sink or in the toilet bowl) or in household waste. Ask your health care professional how to get rid of unused or outdated medications.

What special precautions should I follow while using Bensedin?

Consult your doctor before taking Bensedin in order to find out if you are allergic to it, or to other benzodiazepines (e.g., alprazolam, lorazepam). Bensedin may contain inactive ingredients, which can cause allergic reactions. Talk to your doctor before you start using Bensedin 10mg if you have: glaucoma (narrow-angle), a certain muscle disease (myasthenia gravis), breathing trouble during sleep (sleep apnea). The use of Bensedin can make you dizzy, drowsy or cause blurred vision. People driving or conducting activities which require alertness or clear vision should exercise caution in using alprazolam.

Avoid the use of Bensedin in the following cases: if you have hypersensitivity to diazepam and any other benzodiazepines, myasthenia gravis, severe chronic hypercapnia, specifying a history of alcohol or drug dependence (except for acute withdrawal), pregnancy – should not be used in the 1 trimester of pregnancy, except in cases of extreme necessity, drinking alcohol.

Bensedin side effects

Side effects of Bensedin 10mg which may occur are drowsiness, dizziness, muscle weakness, confusion, depression, blurred vision, diplopia, dysarthria, headache, tremor, ataxia, in single cases – a paradoxical response: excitement, anxiety, sleep disturbances, hallucinations. It is always recommended to talk to your doctor if you encounter any of the side effects. Medical attention should be sought immediately in case signs of an allergic reaction occur such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

What should I do in case of an overdose?

In case of overdose treatment should be taken: induction of vomiting, and the appointment of activated charcoal (if the patient is conscious), gastric lavage through a tube (if patient is unconscious), symptomatic therapy, monitor vital functions: respiration, pulse and blood pressure should be monitored, if necessary – artificial ventilation.

An overdose of Bensedin is seldom life-threatening: if Bensedin is taken alone, but may lead to areflexia, apnea, hypotension, cardiorespiratory depression, and coma. Overdose may include one or more of the following symptoms: somnolence, confusion, coma, and diminished reflexes. With the development of excitation, barbiturates should not be used. In the hospital, conditions used a benzodiazepine receptor antagonist flumazenil as a specific antidote. Hemodialysis is ineffective. Benzodiazepine respiratory depressant effects are more serious in patients with respiratory disease. That is prohibited to take Bensedin with alcohol, because benzodiazepines increase the effects of another central nervous system (CNS) depressants, including alcohol.

Does Bensedin have any interaction with other drugs?

Bensedin may interact with other drugs, including prescription and over-the-counter medicines, vitamins and herbs. Be aware that if you are taking these drugs together, such interaction can be harmful and can cause serious side effects. Taking Bensedin with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects.

Consult your doctor about all the medicines you use. Examples of the drugs which should not be taken concomitantly with Bensedin: sleeping pills, narcotic pain medicine, muscle relaxer, medicine for anxiety, depression or seizures, cimetidine, omeprazole, phenytoin, an antibiotic-clarithromycin, erythromycin, telithromycin, itraconazole, ketoconazole, voriconazole. Heart or blood pressure medication such as diltiazem, nicardipine, quinidine, verapamil, HIV/AIDS medicine such as – atazanavir, delavirdine, fosamprenavir, indinavir, nelfinavir, saquinavir, ritonavir. 

Does Bensedin have any interaction with diseases?

Before using Bensedin 10mg, tell your doctor if you are allergic to it or to other benzodiazepines. Inform your doctor if you have any other allergies. Bensedin 10mg should not be used if you have certain medical conditions. Consult your doctor if you have: glaucoma, a certain muscle disease (myasthenia gravis), breathing trouble during sleep (sleep apnea), liver disease, kidney disease, lung/breathing problems, drug or alcohol abuse.

Additional information

Bensedin (Diazepam) 10mg

10, 50, 100